The Anti-Inflammatorily potential of Fruit and Vegetable Concentrates.
31 May 2010
J.Valverde
Systemic Inflammation (SI) is defined as the inflammation caused by the release of pro-inflammatory small proteins (cytokines) from immune-related cells and the chronic activation of the innate immune system. The release of these compounds can take place as a results of external (biological or chemical agents) and/or internal (genetic mutations) factors.
Chronic Inflammation contributes to an increased risk for developing poor healthy conditions (chronic conditions) such as cardiovascular disease, diabetes and cancer.
Inflammation in a system (human or animal) can be studied by the measurement of inflammation markers in blood and other tissues (inflammatory load).
A recent study conducted in the USA, at the University of South Carolina, evaluating several markers for systemic inflammation from healthy adults. The study tested two different formulations of encapsulated fruit and vegetables concentrates; one with only fruit and vegetables (FV) and the other one with fruit and vegetables with added berry powders (FVB).
Researchers used a double-blind, placebo controlled approach, 117 subjects were randomly given FV, FVB or the placebo.
Results show that some important inflammatory biomarkers such as Monocyte Chemotactic Protein-1, Macrophage Inflammatory Protein 1-beta, and RANTES levels were significantly reduced and superoxide dismutase and micronutrient levels were significantly increased in subjects consuming both FV and FVB, relative to placebo.
These findings suggest a potential health benefit by consuming fruit and vegetable juice concentrates.
This study is in agreement with a recent worked using nutrigenomics conducted in the University of Navarra in Spain.
Click here for further information in this study,
or vist: http://www.ipfn.ie/news/2010/05/27/nutrigenomic-study-supports-the-5-a-day-recommenda/
For further details on this study please see:
Yu, J.; Xiangli, C.; Udai, P. S.; Alexander, A. C.; Brook, H.; Philip, C.; Anne, B. H.; Venkata, K.; Brandy, S.; Suresh, R. V.; Thomas, G. H.; James, R. H.; Lorne, J. H., Systemic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate. Molecular Nutrition & Food Research
Click here for further information in this study.
